Bunga telang populer dikonsumsi dalam bentuk seduhan minuman hangat. Selain itu, bunga ini juga banyak dimanfaatkan sebagai pewarna alami. Warna alami biru dari bunga telang dihasilkan dari senyawa-senyawa bioaktif yang terkanudng dialamnya. Bunga telang dikenal dengan kandungan senyawa bioaktifnya yang banyak memberikan manfaat agar tubuh tetap sehat. Menurut penelitian, senyawa-senyawa tersebut, dapat mencegah zat jahat yang akan masuk ke tubuh kita hingga mengurangi zat tidak baik yang dapat merugikan kesehatan kita. Apa saja senyawa-senyawa baik itu? Mari kita simak di penelitian berikut.
Judul
Senyawa Bioaktif Bunga Telang yang Bersifat Antioksidan, Antelmintik, Antihipertensi, Penghambat Aktivitas Enzim Amilase, Glukosidase serta Senyawa yang dapat Mengurangi Kolesterol LDL dan Oksidasi yang Diinduksi DNA
Abstract The purpose of this study was to use a statistical approach to optimise the experimental conditions regarding the extraction of bioactive compounds, and to analyse the in vitro functional properties of crude lyophilized extracts (CLE) and partially purified (PPE) extracts of Clitoria ternatea petals. The results showed that the factors of temperature and time influenced the extraction of phenolic compounds, antioxidant activity and the physicochemical parameters. Simultaneous optimisation showed that the same levels of bioactive compounds were extracted when using temperatures from 11.7 to 68.3 °C and times from 8.47 to 51.12 min. Principal component analysis revealed the experimental conditions that provided the extraction producing the highest level of phenolic content (40 °C/30 min). The CLE showed antimicrobial activity; protective effect against hemolysis of erythrocytes; inhibition of α-amylase, α-glucosidase and angiotensin-I-converting (ACE-I) enzymes; and inhibition of lipid peroxidation. The CLE and PPE demonstrated oxygen radical absorption capacity; inhibition of DNA strand scission; inhibition of LDL cholesterol oxidation; intracellular antioxidant activity against reactive oxygen species (>100 μg/mL); and no cytotoxicity (IC50, GI50 and LC50 > 900 μg/mL) against A549, HCT8 and IMR90 cell lines.
